Cymbalta (duloxetine) is a selective serotonin and norepinephrine reuptake inhibitor intended for the treatment of depression, generalized anxiety disorder, pain and tingling caused by diabetic neuropathy and fibromyalgia. If you are younger than 24 taking this medicine may be related to developing some serious psychiatric side effects. Therefore you will be required to show up for your doctor's appointments regularly to make sure your treatment is going just as planned and you are benefitting from it. While taking Cymbalta, especially at the beginning of your treatment, you may have some of the side effects mentioned below: nausea, vomiting, constipation, diarrhea, heartburn, stomach pain, decreased appetite, dry mouth, dizziness, headache, weakness, drowsiness, muscle cramps, changes in sexual ability, and uncontrollable shaking. If you are on any drugs from the groups listed below it's important that you let your health care provider know about it before asking for a prescription: sedatives, anticoagulants, diuretics, cimetidine, sleeping pills, selective serotonin reuptake inhibitors, proton pump inhibitors, antidepressants, lithium, quinolone antibiotics, medications for anxiety, tranquilizers, nausea medications, high blood pressure, mental illness, medications for migraine headaches, nonsteroidal anti-inflammatory drugs, and medications for irregular heartbeat. In some cases you may need a dose adjustment or an alternative method of treatment will be found.